Manuela A. Orjuela, M.D., Sc.M.,
Assistant Professor of Clinical Public Health
(Environmental Health Sciences) and Clinical Pediatrics
(Pediatric Oncology)

Dr. Orjuela received her medical degree at Yale where her research focused on mucocutaneous leishmaniasis in Colombia. Subsequently, she completed her training in Pediatrics at Columbia's Babies and Children's Hospital and her training in Pediatric Oncology at the Memorial Sloan Kettering Cancer Center. She then received a ScM degree in Epidemiology at the Harvard School of Public Health and was a member of the Department of Medicine at the Boston Children's Hospital.

As principal investigator she has been involved in a collaborative research project with the Instituto Nacional de Pediatria in Mexico City where she has been studying risk factors for the development of non-familial retinoblastoma. She is interested in the role that DNA viruses and dietary factors play in oncogenic gene-environment interactions. She is particularly interested in the effects that these interactions may have on health problems that affect underprivileged pediatric populations.

Dr. Orjuela also teaches the course Gene-Environment Interactions in Human Disease, P8301.

Orjuela, M., Molecular Genetics and Hereditary Cancer Syndromes, Ed. Michael Weiner, Pediatric Hematology/Oncology Secrets. Philadelphia, Hanley & Belfus, Inc., 2001 in press.

Orjuela, M., Retinoblastoma, Ed. Michael Weiner, Pediatric Hematology/Oncology Secrets. Philadelphia, Hanley & Belfus, Inc., 2001 in press.

Orjuela, M., Lymphoproliferative Disorders, Ed. Michael Weiner, Pediatric Hematology/Oncology Secrets. Philadelphia, Hanley & Belfus, Inc., 2001 in press.

Orjuela M., Orlow I., Dudas M., Ponce-Castañeda V., Salazar A., Leal C., Ridaura C., Abramson D., Gerald W., and Cordon-Cardo C.. Alterations of Cell Cycle regulators affecting the RB-pathway in non-familial retinoblastoma. Human Pathology 2001 32 (5): 537-44.

Orjuela M, Ponce V, Ridaura C, Lecona, E., Leal, C., Abramson, D., Orlow, I., Gerald W, Cordon-Cardo C, Presence of Human Papilloma Virus in tumor tissue from children with retinoblastoma: an alternative mechanism for tumor development. Clinical Cancer Research 2000 Oct;6(10):4010-6.